Obesity is defined as having an abnormal increase of body fat which is also called adipose tissue mass. An obese person is 20 percent or more above desirable weight. In the last decade obesity has been on the rise in both women and men. Fat distribution can influence a person's risk of disease. Fat carried around the waist and in the abdominal area, characterized by the "apple shape", is associated with an increased risk for many medical problems such as heart disease, cancer, high blood pressure, and diabetes. Fat that is mostly distributed around the buttocks and thighs is associated with a lower risk of developing these diseases. As much as 50 to 75 percent of obesity has genetic influences. Just what those genetic influences are that affect body weight have not been identified. Research points to differences in appetite control and energy expenditure. It is important for obese people not to hold themselves responsible for their condition. Obese people should be evaluated for medical consequences of their obesity. Motivated persons are encourage to enter medically supervised treatment programs that use a multidisciplinary approach to weight loss. Many people are tempted by ads that use celebrities to tout liquid fasting diets for weight loss. Ads claim quick and easy weight loss with use of such products. Very obese patients may be referred to these types of diets. Their diets are carefully supervised by their healthcare provider. Medically supervised fasts are very low calorie diets which provide from 400 to 800 calories per day. While most of these diets are low in calories, the protein provision is very high. The purpose of these diets is to promote fat loss, not muscle loss. The high protein content helps prevent large losses of muscle tissue. Electrolytes, vitamins and minerals are also supplemented. During the holidays or when celebrating, many of us have overeaten. But some people have problems controlling their appetite and end up eating non-stop until eating is interrupted. Binge eating is like bulimia, but does not include purging behaviors. A diagnosis of binge-eating disorder is made when a person binges an average of two days per week over a six month period.
The medications most often used in the management of obesity are commonly known as "appetite suppressant" medications. Appetite suppressant medications promote weight loss by increasing metabolism and by decreasing appetite or increasing the feeling of being full. These medications work by increasing the serotonin and/or catecholamine - two brain chemicals that affect mood, appetite and metabolism. The most recent drug in the fight against obesity is Xenical. A new class of non-systemic anti-obesity drug called lipase inhibitors which act in the gastrointestinal tract to prevent the absorption of fat by about 30 percent. Drugs in this class do not achieve their effect through brain chemistry or central nervous system stimulation. In other words, Xenical is not an appetite suppressant or metabolic inducer. Brand names of the most effective prescription diet medications on the market today are: Phentermine, Adipex-P, Fastin, Ionamin, Bontril, Plegine, Tenuate, Xenical. Several appetite suppressant medications are available to treat obesity. In general, these medications are effective, leading to an average weight loss of five to twenty-two lbs. above that expected with non-drug obesity treatments. People respond differently to appetite suppressant medications, and some people experience more weight loss than others. Some obese patients using medication lose more than 10 percent of their starting body weight- an amount of weight loss that may reduce risk factors for obesity - related diseases, such as high blood pressure or diabetes. Most studies of appetite suppressant medications show that a patient's weight tends to level off after four to six months while still on medication treatment. While some patients and physicians may be concerned that this shows tolerance to the medications, the leveling off may mean that the medication has reached its limit of effectiveness. Based on the currently available studies, it is not clear if weight gain with continuing treatment is due to drug tolerance. Obesity often is viewed as the result of a lack of willpower, weakness, or a lifestyle "choice" - the choice to overeat and under exercise. The belief that persons choose to be obese adds to the hesitation of health professionals and patients to accept the use of long-term appetite suppressant medication treatment to manage obesity. However obesity, is more appropriately considered a chronic disease than a lifestyle choice. Other chronic diseases, such as diabetes, and high blood pressure, are managed by long-term drug treatment, even though these diseases also improve with changes in lifestyle, such as diet and exercise. Although this issue may concern physicians and patients, social views on obesity should not prevent patients from seeking medical treatment to prevent health risks that can cause serious illness and death.
Terms and definitions on this pageFDA
- Food and Drug Administration: A government agency that oversees public safety in relation to drugs and medical devices. The FDA gives approval to pharmaceutical companies for commercial marketing of their products.
Fat blocker
- Drugs that block the absorption of fat or calories, and lose substantial weight.
Overweight
- Weighing more than is normal, necessary, or allowed, especially having more body weight than is considered normal or healthy for one's age or build.
Appetite
- An instinctive physical desire, especially one for food or drink. Decreased desire to eat is termed anorexia, while polyphagia (or "hyperphagia") is increased eating. Disregulation of appetite contributes to anorexia nervosa and cachexia, or oppositely, overeating.
Diabetes
- Any of several metabolic disorders marked by excessive discharge of urine and persistent thirst, especially one of the two types of diabetes mellitus.
Diet
- A regulated selection of foods, as for medical reasons or cosmetic weight loss.
- A solutions designed to reduce or suppress the appetite.
Fat
- Any of various soft, solid, or semisolid organic compounds constituting the esters of glycerol and fatty acids and their associated organic groups.
Obesity
- The condition of being obese; increased body weight caused by excessive accumulation of fat.
Stress
- A state of extreme difficulty, pressure, or strain.
- A physical and psychological response that results from being exposed to a demand or pressure.
Suppress
- To curtail or prohibit the activities of.
- To inhibit the expression of (an impulse, for example).
- To bring to an end forcibly as if by imposing a heavy weight.
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